The core principles of laboratory renovation are safety and compliance, functionality, corrosion resistance and easy cleaning, and system reliability. It follows a five-step process: planning, layout, materials, water, electricity, gas and ventilation, and construction and acceptance, and strictly adheres to standards such as GB 50447 and GB 19489.

A typical complete cleanroom is divided into the following functional areas: clean production area, aseptic operation area, inner and outer packaging area, changing buffer zone (first changing room, second changing room, air shower), cleaning and disinfection area, storage area (raw materials, packaging materials, finished products, and non-conforming products), clean laboratory, equipment room, and office management area.

A complete modular cleanroom is based on a modular enclosure structure and is equipped with personnel and material entry and exit purification equipment. It relies on purification air conditioning, fresh air system and three-stage filtration device to achieve air purification treatment. It is supplemented by pressure difference, temperature and humidity, cleanliness monitoring equipment, clean lighting and disinfection system to ensure stable and controllable environment. At the same time, special purification equipment can be selected according to the production process requirements of various industries. The overall assembly is flexible and full-featured, which can effectively maintain the indoor cleanliness level, pressure gradient and environmental parameters, and meet the requirements of various sterile and dust-free production and experimental use.

Stem cell technology serves as a core pillar in regenerative medicine and precision medicine, and the safety and standardization of its research and application directly depend on the construction level of specialized laboratories. The construction of stem cell laboratories differs from that of ordinary biological laboratories, requiring consideration of four core dimensions: clean environment control, biosafety protection, equipment precision assurance, and a quality management system. It must strictly adhere to relevant national and industry standards, achieving standardization throughout the entire process from site planning to operation and maintenance management. This article, based on relevant industry standards, elaborates on the core points and implementation paths for stem cell laboratory construction, providing a practical construction reference for research institutions, medical institutions, and enterprises.

Animal laboratories are specialized facilities used to raise laboratory animals and conduct animal experiments. Their design quality directly affects the accuracy of experimental results, the health and welfare of animals, and the biosafety of researchers.